What Is GenF20 Plus®?
GenF20 Plus® is a dietary supplement formulated with natural amino acids, peptides, and nutrients designed to support the body’s own production of human growth hormone (HGH) through the pituitary gland, without using synthetic HGH like somatropin¹².
How It Works
The product contains ingredients such as GABA, L-Arginine, L-Glutamine, L-Glycine, L-Ornithine, deer velvet antler, colostrum, and phosphatidylcholine¹². These components are thought to stimulate HGH secretion naturally and improve metabolic signaling through insulin-like growth factor-1 (IGF-1)¹³.
Clinical Evidence & Outcomes
A clinical trial showed that, in individuals aged 40 and above, GenF20 Plus® significantly increased serum IGF-1 levels compared to placebo, while improvements in other markers like energy, sleep, or memory were not statistically significant over 12 weeks⁴.
Users have reported subjective benefits such as better energy, firmer skin, enhanced stamina, improved metabolism, and mood improvements⁵⁶.
Benefits
Potential benefits include:
- Boosted natural HGH and IGF-1 levels in those over 40⁴
- Enhanced skin elasticity, reduced wrinkles, improved hair, nails, and immune support¹²⁷
- Increased energy, vitality, metabolism, muscle tone, and libido¹²⁵
- Better mood, cognitive clarity, and potentially improved sleep quality⁶⁵
Safety & Side Effects
GenF20 Plus® is generally well tolerated: reported side effects include mild digestive issues such as acid reflux, hyperacidity, abdominal pain, headaches, and rashes—all typically resolving on their own⁴⁵⁸. Some sources caution that individuals with diabetes, blood pressure issues, or those on blood thinners should approach with care⁸⁹. While marketed as all-natural and additive-free, there remain small—but important—risks, especially for people with specific health conditions⁸⁹.
Safety Compared with Synthetic HGH
Synthetic HGH injections (like somatropin) are expensive, require medical supervision, and carry risks such as joint pain, insulin resistance, and edema⁹¹⁰. GenF20 Plus® offers a more affordable, no-needle, and lower-risk alternative⁹⁶.
Money-Back Guarantee & Use
GenF20 Plus® is typically a tablet/spray combo: 4 tablets per day (morning and evening) plus oral spray, depending on packaging. Pricing ranges from about $70 for a one-month supply to about $350 for a six-month supply; a ~67-day money-back guarantee is offered¹²⁵.
Summary
GenF20 Plus® is a natural HGH releaser with clinical evidence for boosting IGF-1 in people over 40 and a range of anecdotal benefits—energy, skin health, mood, metabolism, and libido. It’s safe for most users, though mild side effects are possible, and people with certain health conditions should consult a healthcare provider before trying it.
References
- Globenewswire. GenF20 Plus Under Review – Why Choose GenF20 Plus Over The Other Popular HGH Releaser Supplement. April 20, 2025.
- Finance Yahoo. GenF20 Under Review: Best HGH Releaser Supplement. 2025.
- Taylor & Francis Online. Effect of Amino Acids on HGH Production.
- Dovepress. Effect of GenF20 Plus on Serum IGF-1 Levels in Healthy Adults: A Randomized Clinical Trial.
- Reddit. GenF20 Plus Review – The Key to Natural Anti-Aging.
- Amazon Music Podcast. GenF20 Plus Review – Best HGH Releaser on the Market.
- Santelog. GenF20 Plus and Skin Elasticity.
- Innerbody. GenF20 Plus Reviews and Safety Considerations.
- Access Newswire. Safe HGH Support Supplement Shows Real Results.
- Healthline. HGH Side Effects.
