GenuinePurity® Berberine HCL delivers a clinically supported 1,200 mg dose of purified Berberine extracted from the bark and roots of select botanical sources. Enhanced with the hydrochloride (HCL) form for improved absorption, this formula is designed to support metabolic efficiency, healthy blood sugar response, insulin sensitivity, weight management, and sustained daily energy.
Try GenuinePurity™ products RISK FREE for 97 days and if they do not work for you, send back the empty containers and we will issue you a prompt, hassle-free refund.
A Time-Tested Botanical for
Modern Metabolic Health
Berberine is a naturally occurring bioactive compound concentrated in plants such as barberry, goldenseal, and tree turmeric. Used for centuries in traditional Chinese and Ayurvedic wellness practices, Berberine is now widely studied for its ability to support metabolic health at the cellular level.
Contemporary research shows that Berberine activates AMPK (AMP-activated protein kinase)—often referred to as the body’s “metabolic master switch.” AMPK plays a central role in regulating glucose metabolism, fat utilization, and cellular energy balance.
Berberine HCL is the most extensively researched and bioavailable form of Berberine. By binding Berberine to hydrochloride, stability and absorption are significantly improved. GenuinePurity® Berberine HCL provides a robust 1,200 mg serving of this highly bioavailable form for consistent metabolic support.
Supports:
Metabolic Health
Blood Sugar Balance
Weight Management
Daily Energy
Transparency You Can Trust
Certificate of Analysis
Many supplement labels don’t always reflect what’s inside the bottle. That’s why every GenuinePurity® product is verified by independent laboratories.
We encourage reviewing a Certificate of Analysis (COA) before purchasing any supplement—ours or anyone else’s—to ensure quality and authenticity.
Key Health Benefits
Blood Sugar Support
Helps improve cellular glucose uptake and utilization, supporting healthier fasting and post-meal blood sugar levels.
Insulin Sensitivity
Encourages improved responsiveness to insulin, helping reduce insulin resistance and easing metabolic strain on the pancreas.
Fat Metabolism
& Weight Management
Supports the body’s ability to burn stored fat and limit new fat accumulation—especially in the abdominal region.
Cholesterol & Lipid Balance
Helps support healthy cholesterol levels by lowering LDL and triglycerides while promoting HDL balance.
This clinically studied amount is designed to deliver effective metabolic support with optimal bioavailability.
97-Day Satisfaction Guarantee
Every GenuinePurity® product includes a 97-day satisfaction guarantee. If you’re not satisfied, simply return your order for a full refund.
Clean, Responsible Formulation
We combine ethically sourced ingredients with modern formulation science to support optimal absorption and cellular effectiveness.
Made in the USA
Manufactured in cGMP-certified facilities in the United States to meet strict quality standards.
Activate the Body’s Metabolic “Master Switch”
AMPK is a key enzyme responsible for regulating glucose metabolism, fat burning, and cellular energy balance. Research shows that Berberine naturally stimulates AMPK activity, creating metabolic effects similar to those seen with exercise or calorie restriction.
Once activated, AMPK signals cells to increase energy efficiency, burn stored fat, and improve glucose utilization—supporting comprehensive metabolic health.
“Berberine activates AMPK.”
ScienceDirect
GenuinePurity® Berberine HCL
Precision-Formulated for Results
Developed in the USA by experts with over 25 years of experience, GenuinePurity® Berberine HCL is engineered for maximum purity, potency, and performance.
Each capsule delivers targeted metabolic support without stimulants or harsh additives.
Comprehensive Metabolic Support
Blood Sugar Support
By activating AMPK, Berberine HCL helps regulate glucose absorption, utilization, and liver glucose output—supporting stable energy and fewer post-meal crashes.
Improved Insulin Response
Supports healthier insulin signaling, allowing glucose to enter cells more efficiently and reducing metabolic stress.
Fat Utilization & Weight Control
Encourages fat burning while slowing the formation of new fat stores—supporting natural, sustainable weight management.
Cholesterol & Lipid Regulation
Supports balanced lipid metabolism by helping reduce LDL and triglycerides while encouraging healthier HDL levels.
Cellular Energy & Vitality
AMPK activation enhances mitochondrial efficiency, helping deliver steady energy to muscles, organs, and the brain for improved stamina and mental clarity.
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